The problem we solve: Current HAART therapy reduces the viral load to undetectable level. But virus persists as provirion in CD4+ and other infected T lymphocytes. Currently there is no drug that targets this provirion. Also decreased CD4 cells and CD4/CD8 cell ratios persists in spite of treatment causing increased infection, malignancy and non-aids morbidity and mortality. Coronavirus infection is also characterized by immune cell dysregulation. decreased Cd4 and Cd8 with lymphopenia, and neutropenia.
About our solution: This treatment raises CD4 T cells and normalizes CD4/CD8 T cell ratios. We want to start feasibility study to show if these drugs are effective in small group of patients. We need to come up with a chemical entity and we have already spoken with a team of scientist who have agreed to work on this project. In our small observation in few patients we have found vanadium compounds are highly active against HIV and hepatitis B,coronavirus,SARS,influenza and parainfluenza and dengue. We would like to develop and start a new clinical trial to test our product.Progress to date:
We did observational studies in small pool of 13 subjects and they have shown dramatic increases in CD4+ cells count quickly in subjects who were taking vanadium complexes than in patients who were not. Also the CD4/CD8 T cell ratio improved quickly than cohorts. Also increases and normalizations of other cell lines such as platelets, neutrophils, monocytes and erythroid cells.The cellulal immune parameter improvement is sustained and persist even after discontinuing the oral treatment in some patients.These effects resulted in reduced frequency of other bacterial,fungal and viral infections. Patients are able to lead normal life with less visits to the hospital visits. Please see our video for discussion on this topic.
Creator: Enrique Gutierrez
Education: Medical,Tulane University, USA & U.Central
Bio: Physician practicing in Kissimmee for over 20 years. Specialize in treating patients with HIV. Completed a specialty fellowship in Allergy and Immunology and Endocrinology at the prestigious Tulane University. Tulane University is one of the top endocrinology programs in the nation attending Tulane gave him the opportunity to train under Nobel Prize winning academicians.Also trained under the founder of the American Academy of Allergy and Clinical Immunology. During his time there he conducted and published ground breaking research in the area of neuro endocrinology and neuro immunology. He has led many pharmaceutical clinical trials and collaborated in developing new drugs with different pharmaceutical companies . His present research is primarily focused on vanadium compound and micronized glyburide for the treatment of HIV and other viral diseases.
Hospital Affiliation: Epigene Channel
Title: Founder & President
Advanced Degree(s): MD
Dr., M.B.B.S., C.T.D.M
Biography: Dr.Dawood is a Physician and Clinical researcher. He has experience in managing several investigator-initiated studies and held research job positions at USC, UCSC, VA SFO, collaborated on many research/clinical trials with reputed universities like Stanford, Harvard etc., expert in managing day- to-day clinical trial activities, and providing support for regulatory filings.
Advanced Degree(s): M.B.B.S., C.T.D.M
Life Sciences Scientist-Virology, Tropical Diseases, immunology Research, PhD
Biography: Professor at the University of Texas, in San Antonio Texas. He has a particular interest in virology and tropical diseases.
Title: Life Sciences Scientist-Virology, Tropical Diseases, immunology Research
Advanced Degree(s): PhD
COVID Problem We Address
The main issue with the Covid-19 pandemic is fear of the devastating consequences of the infection due to absence of immediate acting effective treatment. This therapeutic approach results in immediate positive results against Corona Virus(SARS) both in vitro and in vivo and can free us from the fear while defeating the virus.
Our COVID Solution
Vanadium based metalorganic compounds have been shown in vitro and in vivo to be efficacious at destroying Corona Virus (Sars) as published in scientific journals. Vanadium compounds have also been shown to be effective in vitro and in vivo against dengue, influenza and parainfluenza as well as HIV. The enhanced Vanadium complex being used in this proposal has demonstrated extraordinary efficacy in human subjects with HIV in our pre-clinical study. The treatment can safely destroy corona virus immediately if administered orally and or intravenously.
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